Details
How Naturight Works:
Naturight has been designed to quickly, gently and partially neutralize stomach acid so there is no rebound acid production. Naturight works to eliminate just enough stomach acid at the LES Valve to provide immediate relief of symptoms. Naturight works differently from other OTC treatments because it eliminates heartburn symptoms but leaves enough stomach acid present for proper digestion and nutrient absorption. Naturight works to reduce inflammation of the esophagus, protect and soothe the mucous membranes of the stomach, reduce excess acidity, ease nausea and promote healthy tone and peristalsis of the entire digestive tract.
How Naturight is Different from other OTC Treatments
Certain levels of stomach acid are necessary to promote healthy digestion and to eliminate harmful bacteria that are commonly ingested with food. Naturight Natural Antacid leaves enough stomach acid to encourage optimal digestion and nutrient absorption while allowing good bacteria in the stomach to thrive, providing a powerful defense against a host of serious and degenerative illnesses.
Instructions
At the first sign of heartburn symptoms, chew 1-2 Tablets thoroughly before swallowing for instant relief. Although it is safe to do so, it is not recomended that you chew more than 8 tablets in a 24 hour period in order to maintain enough stomach acid for optimal digestion.
Ingredients
Active Ingredients:
Calcium Carbonate 200mg per tab
Magnesium Glycinate 70mg per tab
Inactive Ingredients:
Acacia gum, Aloe, Cellulose, Ginger, Licorice DGL, Magnesium Stearate, Marshmallow, Meadowsweet, Natural Flavors, Parsley, Peppermint, Silica, Stevia, Xylitol.
WARNINGS:
Ask a doctor or pharmacist before use is you are presently taking a prescription drug. Antacids may interact with certain prescription drugs.
Do not use if you are allergic to aspirin or other salicylates.
Consult your health care practitioner before use if pregnant or breastfeeding.
Keep this and all drugs out of reach of children
Not safe for pets - Contains Xylitol
Understanding Your Heartburn
Why Do I Get Heartburn?
Shortly after you eat, a small valve known as the Lower Esophageal Sphincter (LES) opens to allow food to pass into the stomach. Once the food has passed, the valve closes to prevent stomach acid and bile salts from entering back up the esophagus, which does not have the same protective lining found in the stomach. If the valve relaxes abnormally, malfunctions, or becomes weakened, stomach acid can back up, or reflux into the esophagus, causing the symptoms of heartburn. Heartburn that occurs frequently may be considered Gastroesophageal Reflux Disease (commonly known as GERD), and can eventually lead to more serious health problems.
Understanding Other Heartburn Treatments
Acid Blockers
Acid blockers, known as H2 Antagonists or Proton Pump Inhibitors, prevent or turn off completely the production of acids in the stomach, providing transient relief symptoms. When the stomach is in a state of having no stomach acid present at all, normal digestion is interrupted, nutrients are lost and harmful bacteria may be allowed to thrive, contributing to the occurrence of a host of secondary diseases.
Acid rebound production may occur when these medications are stopped to compensate for the lack of acid present in the stomach causing heartburn symptoms to return. Traditional acid neutralizers, such as Tums and Rolaids, rapidly raise the pH in the stomach, effectively neutralizing most of the acid in the stomach. Because these products address only the symptoms of heartburn and not the cause, symptoms often recur, and the product must be used again and again. Overuse of these products can cause problems such as constipation or diarrhea, exacerbation of hypertension, interaction with other meds or foods, or in worse cases, metabolic alkalosis. They also trigger an “acid rebound” reaction when use is discontinued thereby making the next acid indigestion attack even worse than the last. (1, 2)
H2 Blockers & Proton Pump Inhibitors
Gastric acid inhibiters, such as Prilosec, Tagamet, Nexium, etc, also known as H2 blockers and proton pump inhibitors (PPIs) work by blocking the production of acid in the stomach at the cellular level so that acid production is drastically reduced.
These products can have many harmful side effects and disrupt normal digestion leading to malabsorption and malnutrition. By destroying the “acid barrier”, our first line of defense against harmful bacteria from the nose and mouth, acid blockers can leave one vulnerable to serious bacterial infections such as clostridium difficile, salmonella, enterobacter, and staphylococcus (10, 13). This can lead to an increase in pulmonary infections (11) and may increase one’s risk of cancer (12).
There is some evidence that decreasing stomach acid over time can lead to the formation of gastric ulcers (13). Both gastric acid inhibiters and traditional acid neutralizers can trigger an “acid rebound” reaction when one discontinues them, effectively exacerbating the cause of the problem while palliating the symptoms (3,13).
Sources
1. Fauci, Braunwald, Isselbacher, Wilson, Martin, Kasper, Hauser, Longo Harrison’s Principles of Internal Medicine. 14th Edition, McGraw-Hill, New York, 1998, p283.
2. Uretsky, Samuel D., “Antacids”, Gale Encyclopedia of Medicine, Gale Group, 2002.
3. Wright, Jonathan V., M.D. and Lenard, Lane, Ph.D., Why Stomach Acid is Good for You, M. Evans and Company, Inc., New York, 2001.
4. Felter, Harvey, M.C., and Lloyd, John Uri, Phr.M., Ph.D., King’s American Dispensatory, Ohio Valley Co., Cincinnati, 1898.
5. Wren, R.C. Potter’s New Cyclopaedia of Botanical Drugs and Preparations, The C.W. Daniel Company, Ltd, Saffron Walden, UK 1988.
6. Blumenthal, et al, ed. The complete German Commission E Monographs. Trans. S. Klein, American Botanical Council, Austin, Texas, 1998.
7. Natural Medicines Comprehensive Database, Therapeutic Research Faculty, Stockton, CA, 1999.
8. Gruenwald J, Brendler T, Jaenicke C, eds., PDR for Herbal Medicines, 1st Edition, Medical Economics Company, Montvale, NJ, 1
9. Skenderi, Gazmend, Herbal Vade Mecum, Herbacy Press, Rutherford, NJ, 2003.
10. Dial S., et al. “Risk of Clostridium difficile diarrhea in hospital in-patients prescribed proton pump inhibitors: cohort and case-control studies.” Canadian Medical Association Journal 171(1)
11. Rousseau, M.C., Catala, A., Blaya, J. “Association between pulmonary and digestive infections in patients receiving gastric acid-lowering medications for a long duration”, Brain Injury, October 2003 17(10):883-7.
12. BBC News “Stomach Pills May Increase Cancer Risk”, http://news.bbc.co.uk/1/hi/health/1764772.stm.
13. “Excessive Growth of Bacteria may also be Major Cause of Stomach Ulcers”, Howard Hughes Medical Institute, January 15, 2002. http://www.hhmi.org/news/merchant.html
14. Davies, W.A. “Controlled trial of a carbenoxolone/alginate antacid combination in reflux oesophagitis”. Curr Med Res Opin 5(8):637-44, 1978 15. Young, G.P. et al “Treatment of reflux oesophagitis with a carbenoxolone/antacid/alginate preparation. A double-blind controlled trial”. Scand J Gastroenterol 21(9):1098-104, 1986.
16. Glick, L “Deglycyrrhizinated liquorice for peptic ulcer”. Lancet 2: 817, 1982.
17. Turpie, A.G., Runcie, J., Thomson T.J. “Clinical trial of deglyrrhizinized liquorice in gastric ulcer”. Gut. 10:299-302, 1969.
18. Kassir, Z.A. “Endoscopic controlled trial of four drug regimens in the treatment of chronic duodenal ulceration”. Ir Med J. 78:153-156, 1985.
19. Russell R.I., Morgan R.J., Nelson L.M. “Studies on the protective effect of deglycyrrhized liquorice against aspirin (ASA) and ASA plus bile acid induced gastric mucosal damage, and ASA absorption in rats”. Scand J Gastroenterol Suppl. 92:97-100, 1984.
20. Dehpour A.R., Zolfaghari M.E., Samadian T., Vahedi Y. “The protective effect of liquorice components and their derivatives against gastric ulcer induced by aspirin in rats”. J Pharm Pharmacol 46:148-9, 1994.
21. Dehpour A.R., Zolfaghari M.E., Samadian T., et al. “Antiulcer activities of liquorice and its derivatives in experimental gastric lesion induced by ibuprofen in rats”. Int J Pharm. 119:133-8, 1995.
22. Baker, M.E. “Licorice and enzymes other than 11 beta-hydroxysteroid dehydrogenase: An evolutionary perspective”. Steroids, 59:136-41, 1994. 23. Mowrey D.B., Clayson D.E., “Motion sickness, ginger and psychophysics”, Lancet, March 20, 655-657, 1982.
24. Grontved, A., et al, “Ginger root against seasickness. A controlled trial on the open sea”, Acta Otolaryngol, 105(1-2):45-49, 1988.
25. Bone M.E., Wildinson D.J., Young J.R., et al, “Ginger root-a new antiemetic. The effect of ginger root on postoperative nausea and vomiting after major gynaecological surgery”, Anaesthesia 45(8):669-71, 1990.
26. Holtmann S, Clarke, A.H., Scherer H., Hohn M., “The anti-motion sichness mechanism of ginger. A Comparative study with placebo and dimenhydrinate”, Acta Otolaryngol (Stockholm), 108(3-4):168-74, 1989.
27. British Herbal Pharmacopoeia 1996 British Herbal Medicine Association, Exeter, UK, 1996.
Why Naturight Natural Antacid is Different than Other OTC Medications
Naturight is a combination of Calcium carbonate and Magnesium glycinate, both approved by the FDA for over-the-counter use as an antacid, but in much smaller amounts than other calcium based antacids. Naturight also has added a combination of herbs that are anti-inflammatory, soothing to the lining of the esophagus and stomach and that tend to decrease the symptoms of heartburn by themselves. In this way Enerhealth intends to prove through clinical trials that Naturight is not only treating the symptoms of heartburn, but is improving and regulating the esophagus, stomach and gut, i.e. treating the causes as well as the symptoms of heartburn. Additionally, Enerhealth intends to prove that Naturight reduces and/or eliminates acid rebound associated with PPIs, H2 Blockers, and acid neutralizers.
Meadowsweet, Filipendula or Spiraea ulmaria, is an herb well-known for its anti-inflammatory and analgesic properties. The first aspirin products were made from an extract of this high salicylate herb Spiraea ulmaria and thus we get the name, aspirin.
Although it is not clear which constituents in Meadowsweet are responsible for its digestive properties, accounts abound in texts, old and new, referring to this plant’s ability to treat heartburn and digestive complaints as well as soothe coughs and bronchitis. (4-7) Our Herbalist has used this herb extensively in clinical practice on dozens of patients, not only to treat heartburn, but to help them overcome the effect of “acid rebound” when trying to come off of acid blockers and acid neutralizers. Through that experience, this herb helps to regulate and normalize acid production in stomach. More research is needed to conclusively prove these findings.
Licorice, Glycyrrhiza glabra, is widely known for its ability to treat gastric ulcers, with similar results as Tagamet and Zantac, but without lowering stomach acid and with fewer side effects.(6,8, 16-18) The glycyrrhetinic acid portion of Licorice root has been found to reduce inflammation and increase healing in cases of esophagitis and esophageal ulcerations, especially when used over time (more than 4 weeks) (14,15). It has also been found to soothe and protect the stomach lining against the damaging effects of prolonged use of aspirin or other NSAIDS (19-21). It is thought that licorice does this by increasing anti-inflammatory prostaglandins (NSAIDs block prostaglandins), stimulating mucous secretion and promoting cell growth of the epithelial lining of the stomach (22). We use its deglycyrrated form, DGL, which removes the side effects of hypertension, hypocalcaemia and fluid retention (9).
Ginger root, Zingiber officinale, is best known for its ability to combat nausea and dizziness due to motion sickness, morning sickness and stomach flu (23-25). It was discovered that ginger’s anti-nausea mechanism is not due to its effect on the central nervous system, as is the case with conventional anti-motion sickness drugs, but is due to its influence on the gastric system, i.e. the absorption and neutralization of gastrointestinal toxins and acid (23, 26). Ginger is important in this formula, not only for nausea relief, but for its carminative (eliminates intestinal gas) and spasmolytic (relaxes intestinal spasms) properties (27).
Marshmallow, Althaea officinalis, is added to soothe and restore the epithelial lining of the stomach and gastrointestinal tract (4- 9).
Peppermint, Mentha piperita, has a long history of use as a spasmolytic in digestive complaints, especially dyspepsia, nausea and gastritis. In vitro and animal studies indicate that its antispasmodic effects result from a direct action on the digestive tract smooth muscle similar to calcium antagonist activity (7).
Parsley, Petroselinum crispum act as digestive agents to still spastic discomfort of the upper GI tract (5,6,9).
Sources
1. Fauci, Braunwald, Isselbacher, Wilson, Martin, Kasper, Hauser, Longo Harrison’s Principles of Internal Medicine. 14th Edition, McGraw-Hill, New York, 1998, p283.
2. Uretsky, Samuel D., “Antacids”, Gale Encyclopedia of Medicine, Gale Group, 2002.
3. Wright, Jonathan V., M.D. and Lenard, Lane, Ph.D., Why Stomach Acid is Good for You, M. Evans and Company, Inc., New York, 2001.
4. Felter, Harvey, M.C., and Lloyd, John Uri, Phr.M., Ph.D., King’s American Dispensatory, Ohio Valley Co., Cincinnati, 1898.
5. Wren, R.C. Potter’s New Cyclopaedia of Botanical Drugs and Preparations, The C.W. Daniel Company, Ltd, Saffron Walden, UK 1988.
6. Blumenthal, et al, ed. The complete German Commission E Monographs. Trans. S. Klein, American Botanical Council, Austin, Texas, 1998.
7. Natural Medicines Comprehensive Database, Therapeutic Research Faculty, Stockton, CA, 1999.
8. Gruenwald J, Brendler T, Jaenicke C, eds., PDR for Herbal Medicines, 1st Edition, Medical Economics Company, Montvale, NJ, 1
9. Skenderi, Gazmend, Herbal Vade Mecum, Herbacy Press, Rutherford, NJ, 2003.
10. Dial S., et al. “Risk of Clostridium difficile diarrhea in hospital in-patients prescribed proton pump inhibitors: cohort and case-control studies.” Canadian Medical Association Journal 171(1)
11. Rousseau, M.C., Catala, A., Blaya, J. “Association between pulmonary and digestive infections in patients receiving gastric acid-lowering medications for a long duration”, Brain Injury, October 2003 17(10):883-7.
12. BBC News “Stomach Pills May Increase Cancer Risk”, http://news.bbc.co.uk/1/hi/health/1764772.stm.
13. “Excessive Growth of Bacteria may also be Major Cause of Stomach Ulcers”, Howard Hughes Medical Institute, January 15, 2002. http://www.hhmi.org/news/merchant.html
14. Davies, W.A. “Controlled trial of a carbenoxolone/alginate antacid combination in reflux oesophagitis”. Curr Med Res Opin 5(8):637-44, 1978 15. Young, G.P. et al “Treatment of reflux oesophagitis with a carbenoxolone/antacid/alginate preparation. A double-blind controlled trial”. Scand J Gastroenterol 21(9):1098-104, 1986.
16. Glick, L “Deglycyrrhizinated liquorice for peptic ulcer”. Lancet 2: 817, 1982.
17. Turpie, A.G., Runcie, J., Thomson T.J. “Clinical trial of deglyrrhizinized liquorice in gastric ulcer”. Gut. 10:299-302, 1969.
18. Kassir, Z.A. “Endoscopic controlled trial of four drug regimens in the treatment of chronic duodenal ulceration”. Ir Med J. 78:153-156, 1985.
19. Russell R.I., Morgan R.J., Nelson L.M. “Studies on the protective effect of deglycyrrhized liquorice against aspirin (ASA) and ASA plus bile acid induced gastric mucosal damage, and ASA absorption in rats”. Scand J Gastroenterol Suppl. 92:97-100, 1984.
20. Dehpour A.R., Zolfaghari M.E., Samadian T., Vahedi Y. “The protective effect of liquorice components and their derivatives against gastric ulcer induced by aspirin in rats”. J Pharm Pharmacol 46:148-9, 1994.
21. Dehpour A.R., Zolfaghari M.E., Samadian T., et al. “Antiulcer activities of liquorice and its derivatives in experimental gastric lesion induced by ibuprofen in rats”. Int J Pharm. 119:133-8, 1995.
22. Baker, M.E. “Licorice and enzymes other than 11 beta-hydroxysteroid dehydrogenase: An evolutionary perspective”. Steroids, 59:136-41, 1994. 23. Mowrey D.B., Clayson D.E., “Motion sickness, ginger and psychophysics”, Lancet, March 20, 655-657, 1982.
24. Grontved, A., et al, “Ginger root against seasickness. A controlled trial on the open sea”, Acta Otolaryngol, 105(1-2):45-49, 1988.
25. Bone M.E., Wildinson D.J., Young J.R., et al, “Ginger root-a new antiemetic. The effect of ginger root on postoperative nausea and vomiting after major gynaecological surgery”, Anaesthesia 45(8):669-71, 1990.
26. Holtmann S, Clarke, A.H., Scherer H., Hohn M., “The anti-motion sichness mechanism of ginger. A Comparative study with placebo and dimenhydrinate”, Acta Otolaryngol (Stockholm), 108(3-4):168-74, 1989.
27. British Herbal Pharmacopoeia 1996 British Herbal Medicine Association, Exeter, UK, 1996.
